EYE AND GLAUCOMA RESEARCH
Designation: Head of Molecular and Cellular Research
Department: Clinical Neuroscience
In 2000, he received his Pharm.D. degree from the University of Lisbon, Portugal. During the same year, he enrolled in a doctoral program at the Karolinska Institute. His masters and doctoral studies focused on how oxygen levels mediate protein degradation of the hypoxia-inducible factors. These studies culminated in a Licentiate in 2005, and subsequently a Ph.D. in 2009, both in Cell and Molecular Biology.
Following his Ph.D., he continued at the Karolinska Institute as a postdoctoral fellow at the department of Clinical Neurosciences. During his postdoc, he investigated the cellular and molecular mechanisms involved in neovascular age-related macular degeneration, a particularly incident sight-threatening disease. My research elucidated a central role for hypoxia-inducible factor-1alpha in this disease.
His research is centered on cell-based and gene therapy strategies to target the hypoxia-inducible factors as potential therapeutic agents in ocular vascular diseases.
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