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We are pleased to make your acquaintance. On behalf of the editors of our esteemed journals it is an honor to invite researchers of every field including Science, Technology, Engineering and Mathematics (STEM) to publish their findings with us. Join hands with Boffin Access on a journey to disseminate your research and expertise to those in need across the globe through Open Access.

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Come and join Boffin Access Limited. in expanding and contributing to the wealth of human knowledge. With our platform we hope to maximize the reach of your unique expertise and skill set to inspire and guide future generations onto a path of creative and sustainable innovation.

Recently Published Articles


Evaluation of Freezing Capacity of a Conceptual Adaptive Food Preservation System (AFPS) Appliance in the Context of IEC 62552 Standards

Preserving food item individually in an Adaptive Food Preservation System (AFPS) package is a new concept. Before completing a product commercialization process, AFPS packages must be certified against mandatory standards like IEC 62552. This paper evaluates two key aspects of energy efficiency against the IEC standard. Internal volume and storage capacity are evaluated qualitatively. Freezing capacity will be evaluated by experimentation with a simulated AFPS package. The result is verified by an analytical model. Error source and rectifications are identified. The usable storage capacity with AFPS packages is larger than that in a typical refrigerator if both have the same internal volume. Experimentation and theoretical model analysis have demonstrated that the freezing times are 3.18 and 3.32 hours, respectively, which can be considered agreeable. The freezing capacity of the conceptual AFPS package is found to comply with the IEC standard.

Corresponding author: Andrew H.F Tsang, Department of Industrial & System Engineering, Hong Kong Polytechnic University, General PO Box 10099, Central, Hong Kong, Tel: +852 6112 2960, E-mail: tsangandrew.hf@gmail.com

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Unstable Multi-Level Ligamentous Injury of the Cervical Spine in an Adolescent

Purpose: Unstable ligamentous injuries to the cervical spine are unusual within the adolescent population, being more common in younger children. Multi-level unstable ligamentous injuries are rare. Current radiological screening techniques are performed supine. These may miss the dynamic instability of such injuries when under physiological load.

Methods: We examine a case report of an adolescent suffering an atypical multi-level disc-and-ligamentous injury of the cervical spine during rugby.

Results: The instability of the injury at multiple levels was not obviously apparent on CT, MRI or supine radiographs, as per standard screening protocols, and was only revealed via sequential regular erect radiographs; requiring significant intervention in the form of sequential operations.

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Clinicopathological and Prognostic Outcomes of VEGF Expression in Resected Gastric Cancer Tissues. A Systematic Review

Background: Vascular endothelial growth factor VEGF families have been implicated in prognosis and clinicopathological outcomes in patients with gastric cancer. This review aims to assess the relationship of clinicopathological and prognostic outcomes of patients with gastric cancer, present with overexpression of VEGF families in gastric cancer tissues.

Methods: Full-published studies regarding clinicopathological and prognostic outcomes of patients with gastric cancer present with overexpression VEGF families sought through PubMed, MEDLINE, EMBASE and HINARI. The exclusion criteria for the reviewed literature were as follows. (1) The studies involved neoadjuvant or preoperative chemotherapy, chemoradiotherapy and target therapy. (2) Non-English articles. (3) The patients had multiple tumors. (4) The data sample was not reliable (5). The studies analyze the expression of VEGF in blood serum. STATA SE v. 13.1 (STATA_ Corporation, Texas, USA) has been used to analyze data. Statistical significant p-value was taken to be P<0.05 and two sided alpha of 5% implemented to determine confidence intervals and p-values. The outcomes of interest were clinicopathological and prognostic outcomes.

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Synaptic-Adhesion Molecules Neurexin 1 and Neuroligin 1 as Novel Prognostic Factors in Oral Squamous Cell Carcinoma

Background: Synaptic adhesion molecules regulate synapse development and maintenance. Neurexins and neuroligins have been implicated in psychiatric disorders, and shown that they are related to vascular system and carcinomas in recent studies. In the present study we focused neurexin 1 and neuroligin1, and investigated the relationship between those two molecules expression and clinical features of oral cancer.

Materials and methods: Fifty-six biopsy samples from oral squamous cell carcinomas (OSCCs) were analyzed semi quantitatively by immunohistochemistry. Correlations between the expression level of neurexin 1, neuroligin 1, p53, Ki67 and the clinical features of OSCCs were statistically analyzed.

Corresponding author: Toru Yanagawa, D.D.S., M.D., Ph.D., Department of Oral and Maxillofacial Surgery, Institute of Clinical Medicine, University of Tsukuba, Tsukuba-shi, Ibaraki-ken, Japan, Phone/fax: 81-29-853-3192, E-mail: ytony@md.tsukuba.ac.jp

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Opioid Withdrawal after Sufentanil-induced Anesthesia

This clinical case reports a withdrawal syndrome following intravenous administration of sufentanil to a young woman for short-term anesthesia. Hypotheses are issued and documented. The first, being the fact that the patient had a low liposuction-related fat mass resulting in fast lipid release of sufentanil. The second was a relative overdose of sufentanil leading to non-release of encephalin.

I observed a morphine withdrawal following a gynecological procedure on a small uterine polyp. Anesthesia procedure consisted of: propofol 200 mg, sufentanil 10 mg, droperidol 1.25 g, administered intravenously. The symptoms observed in the 37-year-old woman, 8 hours after surgery, were: derealization, hyperthermia, paresthesia and myoclonus of the upper and lower limbs, gastric embarrassment [1]. The duration of the symptoms for about 3 hours was more representative of a morphine withdrawal; if some symptoms are closed to a panic attack the duration is different.

Corresponding author: Michel Bourin, Neurobiology of Anxiety and Mood disorders, University of Nantes, 98, rue Joseph Blanchart, 44100, Nantes, France, Tel: 33610858103, E-mail: michel.bourin@univ-nantes.fr

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Falsely Elevated Levels of Pancreastatin, a Neuroendocrine Tumor Marker

Chromogranin A and pancreastatin are neuroendocrine tumor markers. A 69-yearold female presented for diagnosis and management of a potential neuroendocrine tumor related to nausea, vomiting, and diarrhea for over 40 years. Initial neuroendocrine tumor work-up only revealed a slightly elevated chromogranin A level. Computed Tomography (CT) of chest, abdomen, and pelvis did not find neuroendocrine tumors. Her pancreastatin levels were higher than upper limit of normal at one commercial laboratory with a pancreastatin assay developed in-house but entirely normal in another which used a validated assay. The patient in this case illustrates an often-neglected cause of false positive test result, namely, spurious assay. Clinicians need to critically analyze a given test result in the context of clinical history, physical examination findings, other biochemical test and imaging results, and histological evidence, and to determine if an unexpected test result is false positive.

Corresponding author: Run Yu, Division of Endocrinology, UCLA David Geffen School of Medicine, Los Angeles, CA 90095, USA, Tel no: 310-825-7922, Fax no: 310-267-1899, E-mail: runyu@mednet.ucla.edu

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Advanced Oxidation of Contaminants of Emerging Concern: Photocatalysis and Antibiotics

Contaminants of Emerging Concern (CECs) refers to any chemical discovered in water or in the environment that had not previously been detected, or were only present at insignificant levels. CECs is the general term covering a wide class of different types of chemical compounds, including disinfection by-products, endocrine disruptors, industrial chemicals, natural toxins, Persistent Organic Pollutants (POPs), Flame Retardants (FRs), Artificial Sweeteners (ASWs), Pesticides, Pharmaceuticals and Personal Care Products (PPCP) [1-2]. Pharmaceuticals are among the prime examples of emerging contaminants since up to 90% of oral drugs pass through the human body and end up in the environment ranging from nanogram per liter (e.g., carbamazepine) up to milligram per liter (e.g., acesulfame) concentration levels [2]. Antibiotics are the most consumed group of pharmaceuticals and their presence in the effluents of urban wastewater treatment plants is associated with Antibiotics Resistance (AR) and Antibiotic Resistance Genes (ARG) transfer [3].

Corresponding author: Sureyya Meric, Namik Kemal University, Environmental Engineering Department Corlu, Tekirdag, Turkey, E-mail: smeric@nku.edu.tr

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Biological Efficiency Testing According ISO 14698-1

The biological collection efficiency of the active multi-nozzle impactor air sampler TRIO. BAS MINI was compared to the efficiency of the slit to agar air sampler called CASELLA type that is used as traditional reference air sampler device. The TRIO.BAS biological efficiency was 82% vs Casella microbial air sampler [1,2]. Considering that the evaluation of biological efficiency between different microbial air samplers is always difficult and relative, the two results can be considered statistically comparable.

Corresponding author: Roberto Ligugnana, Villa Cella Applied Microbiology Laboratory, Environmental Monitoring, State University of Milan, Milan, Italy, Tel no: 39 02 487791, Fax no: 39 02 40 09 00 10, E-mail: roberto.ligugnana@gmail.com

Citation: Ligugnana R, Montagna R (2018) Biological Efficiency Testing According ISO 14698-1. Methods Microbiol Mol Biol 1:103

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Augmenting Activity Recognition with Commonsense Knowledge and Satellite Imagery

Activity recognition gained relevance because of its applications in a variety of fields. Despite relevant improvements, classifiers are still inaccurate in several real-world circumstances or require excessively time-consuming training routines. In this paper we show how satellite imagery and common sense knowledge can be used for improving users’ activity recognition performed on a mobile device. More specifically, we made use a personal device providing a list of candidate user activities instead of only the most probable one. Then, from the GPS location of the user, we (i) extract a list of neighboring commercial activities using a reverse geo-coding service and (ii) classify the satellite imagery of the area with state-of-the-art techniques. The proposed approach uses the ConceptNet network for ranking the list of candidate activities using both additional information. Results show an improvement in activity recognition accuracy.

Corresponding author: Nicola Bicocchi, Department of Information Engineering, University of Modena and Reggio Emilia, Modena, Italy, Tel. No: +393478004903, E-mail: nicola.bicocchi@unimore.it

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Optimization Of Cancer Treatment Through Overcoming Drug Resistance

Cancer Drug resistance is a medical concern that requires extensive research and a thorough understanding in order to overcome. Remarkable achievements related to this field have been accomplished and further work is needed in order to optimize the cure for cancer and serve as the basis for precise medicine with few or no side effects.

Corresponding author: Yahya I. Elshimali, Department of Pathology and Oncology, UCLA School of Medicine & Charles R. Drew, University of Medicine and Science, USA, Tel.: +1-818-515-7618, Fax: +1-818-994-9875, E-mail:elshimali@gmail.com, yahyaelshimali@cdrewu.edu

Citation: Elshimali YI , Wu Y, Khaddour H, Wu Y, Gradinaru D, et al. Optimization Of Cancer Treatment Through Overcoming Drug Resistance. J Cancer Res Oncobiol. 2018 Jan; 1(2):107

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About Boffin Access Limited

Boffin access limited is an emerging Open Access publisher with nearly forty journals spanning several fields of Science, Technology, Engineering and Mathematics (STEM). Our aim is to create an international venue for researchers from all walks of life to share and exchange their findings in order to push the boundaries of current knowledge.

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EDITOR IN CHIEF'S
Invocation to
Scientific Publications

Forthcoming Special Issues

Journal Name: Journal of Cancer Research and Oncobiology (ISSN 2517-7370)
Title: Clinical Translational Research In Breast Cancer
Editor: John Yahya I Elshimali...Read more

Journal Name: Methods of Microbiology and Molecular Biology (ISSN 2517-7435)
Title: CRISPR, Genome Editing and Promotion in Plant Science
Editor: Ali Movahedi...Read more

Journal Name: Journal of Neuroscience and Neurosurgery (ISSN 2517-7400)
Title: Neurobiology of Anxiety and Mood Disorders.
Editor: Michel Bourin...Read more
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