Department of Mechanical Engineering, Babol Noshirvani University of Technology, Iran (Islamic Republic of)
Corresponding author details:
Department of Mechanical engineeringTechnology Development
Babol Noshirvani University of Technology
Iran (Islamic Republic of)
Copyright: © 2020 Sadeghian M. This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 international License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Aneurysms are one of the most catastrophic cerebral emergencies that causes into high
mortality. Clinical observations shed the light on aneurysm development which is reported
that aneurysm is likely to be related to the hemodynamics condition of the blood vessel in
brain. Although the mechanisms of the formation, growth and rupture of aneurysms are not
fully discovered but local hemodynamic crucial factors such as dynamic pressure, wall shear
stress, blood flow velocity, and residence time are thought to play dominant roles in the
growth and initiation of aneurysms, and also the success or failure of aneurysm therapies.
Computational Fluid Dynamics (CFD), a numerical simulation aims to provide data, which
will help in clinical decision in recognizing the aneurysms at risk of rupture and in the
treatment of them.
Aneurysm; CFD; Wall Shear Stress; Blood Flow; Stent; Endovascular Embolization;
Cerebral aneurysms are pathologic dilations of the arterial wall that frequently occurred at or near arterial bifurcations. The exact cause of aneurysm formation remains unclear; but there isevidence that high shear stress and blood velocity may provide the hemodynamic environment fordegenerative vascular injury.
Flow patterns incerebral artery bifurcations and bends have been the subject of
comprehensive investigation [1-3]. The growth of cerebral aneurysm may compress brain
tissues and surrounding nerves which may cause one or more health conditions; including
vomiting, headache, nerve paralysis, seizure and body numbness. When the cerebral
aneurysm ruptures generally causes internal bleeding, in the end which in several cases
causes death. Stroke is one of the prominent reasons of death in the US. Subarachnoid
hemorrhage explains about 7% of stroke cases and most of these cases are caused by
rupture of a cerebral aneurysm . Around 50% of patients with aneurysmal will suffer
serious disability or die as a result of the initial hemorrhage . The flow dynamics of
cerebral aneurysms havebeen studied in numerous experimental models andclinical
studies to investigate the role of hemodynamicforces in the initiation, growth, and rupture
of cerebral aneurysms (Figure 1).